A new long-term animal test from an Italian cancer institute raises serious safety questions about the artificial sweetener aspartame, which is marketed generically as well as under the NutraSweet and Equal brand names. A dozen toxicology and epidemiology experts and the nonprofit Center for Science in the Public Interest are calling on the Food and Drug Administration (FDA) to immediately review the study, which found increases in lymphomas, leukemias, and breast cancers in rats. If FDA concludes that aspartame does cause cancer in animals, the agency is required by law to revoke its approval for the controversial sweetener, which is used in Diet Pepsi, Diet Coke, tabletop packets, and countless other foods. The new study, conducted by the respected Ramazzini Foundation and published in the journal Environmental Health Perspectives, found statistically significant increases in lymphomas and leukemias in rats that were fed as little as 20 milligrams of the sweetener per kilogram of body weight—an amount that’s in the ballpark of what some people consume. The new study is superior to a similar one released in 2005 in that it began exposing the rats to aspartame before their birth.
